Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.69 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120492 | 1.00 | CRBN (0.69) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL8076294 | 0.83 | DDB1 (0.47) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL30828435 | 0.82 | CRBN (1.00) | CRBNDDB1MAPT | |
| SCHEMBL31195523 | 0.81 | CRBN (0.69) | CRBNDDB1ALDH1A1MEN1KMT2A | |
| SCHEMBL31731801 | 0.81 | CRBN (0.69) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL22941454 | 0.81 | CRBN (0.69) | CRBNDDB1MAPTHSD17B10 | |
| SCHEMBL5447073 | 0.81 | CRBN (0.69) | CRBNDDB1KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL30828456 | 0.81 | CRBN (0.97) | CRBNDDB1MAPT | |
| SCHEMBL21995539 | 0.81 | CRBN (0.52) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL31674505 | 0.81 | CRBN (0.52) | CRBNDDB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114521196-A | Bifunctional group degradation agent and use method thereof | 诺华股份有限公司 | 2022-05-20 | — | — | CN | disclosed |