SCHEMBL8076294

SCHEMBL8076294

O=C1CN(c2cccc(O)c2)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 2/20 0.47
CRBN Q96SW2 2/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ESR1 P03372 1/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MCL1 Q07820 1/20 0.42
OPRM1 P35372 1/20 0.41
HPGD P15428 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.40
GRM2 Q14416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701187 0.85 MEN1 (0.46) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL29606370 0.83 CRBN (0.69) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL23120492 0.83 CRBN (0.69) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL7257909 0.81 DDB1 (0.71) DDB1CRBNMEN1KMT2AKDM4E
SCHEMBL1788429 0.79 MEN1 (0.58) DDB1CRBNMEN1KMT2AKDM4E
SCHEMBL5182235 0.79 DDB1 (0.47) DDB1CRBNMEN1KMT2AKDM4E
SCHEMBL3553878 0.79 ALDH1A1 (0.57) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL4539723 0.78 CRBN (0.46) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL746783 0.77 CRBN (0.66) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL10814936 0.77 MAPT (0.60) DDB1CRBNMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6121024-A Halophilic Pseudomonas strain having accession No.NCIM 5109 (ATCC 55940) and a process for preparingD(-)N-carbamoylphenylglycine using said strain COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2000-09-19 US claimed