Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 1.00 |
| ▸ | DDB1 | Q16531 | 15/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30828456 | 0.98 | CRBN (0.97) | CRBNDDB1ADRA2CMAPTALOX5 | |
| SCHEMBL7257909 | 0.83 | DDB1 (0.71) | CRBNDDB1ADRA2CMAPT | |
| SCHEMBL23120492 | 0.82 | CRBN (0.69) | CRBNDDB1MAPT | |
| SCHEMBL31195523 | 0.82 | CRBN (0.69) | CRBNDDB1ALOX5 | |
| SCHEMBL22941454 | 0.82 | CRBN (0.69) | CRBNDDB1MAPTALOX5 | |
| SCHEMBL31731801 | 0.82 | CRBN (0.69) | CRBNDDB1ALOX5 | |
| SCHEMBL29606370 | 0.82 | CRBN (0.69) | CRBNDDB1MAPT | |
| SCHEMBL5447073 | 0.82 | CRBN (0.69) | CRBNDDB1ALOX5 | |
| SCHEMBL30643657 | 0.81 | DDB1 (0.68) | CRBNDDB1MAPT | |
| SCHEMBL25570863 | 0.81 | DDB1 (0.68) | CRBNDDB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |