SCHEMBL29607159

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	1/20	0.51

▸	APLNR	P35414	2/20	0.49

▸	OPRK1	P41145	9/20	0.47

▸	OPRM1	P35372	6/20	0.47

▸	CTSL	P07711	2/20	0.45

▸	CTSS	P25774	2/20	0.45

▸	CTSK	P43235	2/20	0.45

▸	CTSH	P09668	1/20	0.45

▸	PLK1	P53350	1/20	0.45

▸	NPY4R	P50391	3/20	0.44

▸	NPY1R	P25929	2/20	0.44

▸	NPY2R	P49146	2/20	0.44

▸	NPY5R	Q15761	2/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5581709	0.95	MC4R (0.52)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL7531984	0.95	MC4R (0.52)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL30776248	0.94	MC4R (0.45)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL29607754	0.93	APLNR (0.56)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL29607228	0.93	MC4R (0.55)	MC4RAPLNROPRK1OPRM1
SCHEMBL29606819	0.93	APLNR (0.57)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL29607035	0.93	APLNR (0.55)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL30518977	0.93	APLNR (0.52)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL29607506	0.92	APLNR (0.56)	MC4RAPLNROPRK1OPRM1CTSL
SCHEMBL31384591	0.91	MC4R (0.56)	MC4RAPLNROPRK1OPRM1NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220120732-A1	TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES	RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL)	2022-04-21	—	—	US	disclosed