Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 2/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.44 |
| ▸ | CALCR | P30988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531984 | 1.00 | MC4R (0.52) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL29607159 | 0.95 | MC4R (0.51) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL30518977 | 0.90 | APLNR (0.52) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL30454991 | 0.90 | APLNR (0.57) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL31510391 | 0.90 | MC4R (0.51) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL31384591 | 0.89 | MC4R (0.56) | MC4ROPRM1OPRK1APLNR | |
| SCHEMBL31384590 | 0.88 | MC4R (0.54) | MC4ROPRM1OPRK1APLNR | |
| SCHEMBL29607754 | 0.88 | APLNR (0.56) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL30776248 | 0.88 | MC4R (0.45) | MC4ROPRM1OPRK1CTSLCTSS | |
| SCHEMBL29607228 | 0.88 | MC4R (0.55) | MC4ROPRM1OPRK1APLNRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024822-B1 | CD8 AS AN INHIBITOR OF THE CELLULAR IMMUNE SYSTEM | AVIDEX LTD (GB) | 2002-04-10 | — | — | EP | claimed |
| CN-1283120-A | CD8 as inhibitor of cellular immune system | AVIDEKS CO LTD (GB) | 2001-02-07 | — | — | CN | claimed |
| US-20070191278-A1 | CD8 AS AN INHIBITOR OF THE CELLULAR IMMUNE SYSTEM | AVIDEX LIMITED (GB) | 2007-08-16 | — | — | US | disclosed |
| CN-1256147-C | CD8 as inhibitor of cellular immune system | AVIDEKS CO LTD (GB) | 2006-05-17 | — | — | CN | disclosed |
| CN-1283120-A | CD8 as inhibitor of cellular immune system | AVIDEKS CO LTD (GB) | 2001-02-07 | — | — | CN | disclosed |