SCHEMBL29607255

SCHEMBL29607255

CC(C)=C(Br)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPC1 O15118 1/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28741697 1.00 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28741709 0.86 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29608415 0.86 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL16271971 0.79 ALDH1A1 (0.42) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL250085 0.78 ALDH1A1 (0.42) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL30719677 0.75 DYRK1A (0.52) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL6270524 0.75 ALDH1A1 (0.42) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1538379 0.71 ALDH1A1 (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9754019 0.71 ALDH1A1 (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL30438243 0.71 ALDH1A1 (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291593-B2 Compounds for use in catalyst compositions for the production of polyolefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-05-06 US disclosed
EP-4031592-B1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-04-30 EP disclosed
CN-114423769-B Compounds in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2024-04-26 CN disclosed
US-20220356275-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-11-10 US disclosed
EP-4031592-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC Global Technologies B.V. (NL) 2022-07-27 EP disclosed
CN-114423769-A Compounds for use in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2022-04-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356275-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS RPLP0, RPS20, RPS10 ALDH1A1 1508/4885HPGD 3870/4885ALOX15 744/4885
US-12291593-B2 Compounds for use in catalyst compositions for the production of polyolefins RPLP0, RPS20, RPS10 ALDH1A1 1508/4885HPGD 3870/4885ALOX15 744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.