SCHEMBL9754019

SCHEMBL9754019

CC1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
NPC1 O15118 1/20 0.44
PLA2G1B P04054 1/20 0.44
NFKB1 P19838 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5086021 0.96 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30719677 0.82 DYRK1A (0.52) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30438243 0.82 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL18261205 0.82 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1538379 0.82 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL15458052 0.80 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7181544 0.80 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL9754016 0.80 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL5080313 0.80 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL28617997 0.80 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3529283-B1 THERMALLY TUNABLE PHOSPHINIMINE CATALYSTS NOVA CHEM INT SA (CH) 2023-11-29 EP disclosed
US-11760819-B2 Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
CN-109824809-B Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof 三井化学株式会社 2022-06-28 CN disclosed
US-20210122861-A1 ETHYLENE ALPHA-OLEFIN NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2021-04-29 US disclosed
US-10919997-B2 Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2021-02-16 US disclosed
US-20200231620-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2020-07-23 US disclosed
US-10570222-B2 Thermally tunable phosphinimine catalysts NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-02-25 US disclosed
US-20190241683-A1 THERMALLY TUNABLE PHOSPHINIMINE CATALYSTS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2019-08-08 US disclosed
CN-105916888-B The manufacture method of ethylene/alpha olefin polymer 三井化学株式会社 2018-03-16 CN disclosed
EP-3220441-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-09-20 EP disclosed
US-20160347894-A1 ETHYLENE ALPHA-OLEFIN NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2016-12-01 US disclosed
CN-105916888-A Method for producing ethylene/alpha-olefin copolymer 三井化学株式会社 2016-08-31 CN disclosed
CN-100567316-C The high yield of ansa-metallocene and parent ligands thereof improves synthetic CHEVRON PHILLIPS CHEMICAL CO (US) 2009-12-09 CN disclosed
CN-1993373-A Improved synthesis of ansa-metallocene and their parent ligands in high yield CHEVRON PHILLIPS CHEMICAL CO (US) 2007-07-04 CN disclosed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231620-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT ALDH1A1 3318/4885NPC1 1889/4885PLA2G1B 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.