Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779529 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1GAAHSD17B10GLA | |
| Hydrochloric Acid SCHEMBL29175076 | 0.98 | KDM4E (0.49) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL5188827 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL6773955 | 0.81 | EGFR (0.49) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8890863 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL2992806 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10GLA | |
| Hydrochloric Acid SCHEMBL27506548 | 0.80 | EGFR (0.48) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL2125547 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL20563159 | 0.80 | MTNR1A (0.47) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL1882693 | 0.79 | MEN1 (0.53) | KDM4EALDH1A1GAAHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432423-A | NF for treating diseases and disorderskInhibitors of B activity | 拉金德拉·萨哈伊·巴特纳格尔 | 2022-05-06 | — | — | CN | claimed |
| CN-114432423-A | NF for treating diseases and disorderskInhibitors of B activity | 拉金德拉·萨哈伊·巴特纳格尔 | 2022-05-06 | — | — | CN | disclosed |