⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574284 | 0.78 | HTT (0.45) | — | |
| SCHEMBL1359176 | 0.78 | HTT (0.45) | — | |
| SCHEMBL2963080 | 0.77 | CA2 (0.48) | — | |
| SCHEMBL28505920 | 0.76 | — | — | |
| SCHEMBL259989 | 0.76 | — | — | |
| SCHEMBL14693794 | 0.76 | — | — | |
| SCHEMBL6243137 | 0.74 | — | — | |
| SCHEMBL6894525 | 0.74 | HTT (0.47) | — | |
| SCHEMBL4457494 | 0.74 | HTT (0.47) | — | |
| SCHEMBL15751072 | 0.74 | HTT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211858-A1 | TUBULAR SUPRAMOLECULAR POLYMERS | THE JOHNS HOPKINS UNIVERSITY | 2022-07-07 | — | — | US | claimed |
| WO-2020219498-A1 | TUBULAR SUPRAMOLECULAR POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-10-29 | — | — | WO | claimed |
| US-20160220691-A1 | NOVEL SELF-ASSEMBLING DRUG AMPHIPHILES AND METHODS FOR SYNTHESIS AND USE | THE JOHNS HOPKINS UNIVERSITY | 2016-08-04 | — | — | US | claimed |
| US-9180203-B2 | Self-assembling drug amphiphiles and methods for synthesis and use | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-10 | — | — | US | claimed |
| EP-2911701-A1 | NOVEL SELF-ASSEMBLING DRUG AMPHIPHILES AND METHODS FOR SYNTHESIS AND USE | The Johns Hopkins University (US) | 2015-09-02 | — | — | EP | claimed |
| WO-2014066002-A1 | NOVEL SELF-ASSEMBLING DRUG AMPHIPHILES AND METHODS FOR SYNTHESIS AND USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-05-01 | — | — | WO | claimed |
| US-20140113875-A1 | NOVEL SELF-ASSEMBLING DRUG AMPHIPHILES AND METHODS FOR SYNTHESIS AND USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-04-24 | — | — | US | claimed |
| JP-2008510795-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1789091-A2 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | Nicholas Piramal India Limited (IN) | 2007-05-30 | — | — | EP | claimed |
| WO-2006027711-A2 | PRODRUGS AND CODRUGS CONTAINING BIO- CLEAVABLE DISULFIDE LINKERS | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2006-03-16 | — | — | WO | claimed |
| US-20220211858-A1 | TUBULAR SUPRAMOLECULAR POLYMERS | THE JOHNS HOPKINS UNIVERSITY | 2022-07-07 | — | — | US | disclosed |
| US-11160875-B2 | Therapeutic nanofiber hydrogels for local treatment of brain-related diseases | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-11-02 | — | — | US | disclosed |
| WO-2020219498-A1 | TUBULAR SUPRAMOLECULAR POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-10-29 | — | — | WO | disclosed |
| US-20180360987-A1 | THERAPEUTIC NANOFIBER HYDROGELS FOR LOCAL TREATMENT OF BRAIN-RELATED DISEASES | THE JOHNS HOPKINS UNIVERSITY | 2018-12-20 | — | — | US | disclosed |
| US-9987370-B2 | Self-assembling drug amphiphiles and methods for synthesis and use | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| EP-1142490-A1 | Flavouring a foodstuff with compounds containing a sulphur atom linked to two specific atoms or groups | QUEST INTERNATIONAL B.V. (NL) | 2001-10-10 | — | — | EP | disclosed |
| EP-0675712-A4 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS. | HANDELMAN JOSEPH H (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0675712-A1 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS | HANDELMAN, Joseph H. (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5446134-A | Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1995-08-29 | — | — | US | disclosed |
| WO-1994014428-A1 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS | HANDELMAN, JOSEPH, H. (US) | 1994-07-07 | — | — | WO | disclosed |