Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 9/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120540 | 1.00 | DDB1 (0.57) | DDB1CRBNITGB3ITGA2BLMNA | |
| SCHEMBL23120479 | 0.85 | DDB1 (0.56) | DDB1CRBNITGB3ITGA2BALOX15 | |
| SCHEMBL25079571 | 0.83 | TPSAB1 (0.51) | DDB1CRBNMEN1MAPTKMT2A | |
| SCHEMBL30257675 | 0.83 | DDB1 (0.64) | DDB1CRBNLMNAHSD17B10MEN1 | |
| SCHEMBL23120866 | 0.81 | CRBN (0.58) | DDB1CRBNHSD17B10MEN1MAPT | |
| SCHEMBL29606941 | 0.81 | CRBN (0.58) | DDB1CRBNHSD17B10MEN1MAPT | |
| SCHEMBL23120685 | 0.80 | CRBN (0.57) | DDB1CRBNHSD17B10MEN1MAPT | |
| SCHEMBL25247627 | 0.79 | CRBN (0.46) | DDB1CRBN | |
| SCHEMBL24777183 | 0.79 | DDB1 (0.51) | DDB1CRBNALOX15HSD17B10TSHR | |
| SCHEMBL25259486 | 0.79 | HSD17B10 (0.42) | DDB1CRBNALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-114521196-A | Bifunctional group degradation agent and use method thereof | 诺华股份有限公司 | 2022-05-20 | — | — | CN | disclosed |