Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079332 | 0.87 | TPSAB1 (0.61) | TPSAB1TPSD1TPSG1DDB1CRBN | |
| SCHEMBL24530703 | 0.85 | DDB1 (0.50) | DDB1CRBNL3MBTL1MEN1KMT2A | |
| SCHEMBL29607604 | 0.83 | DDB1 (0.57) | DDB1CRBNMEN1KMT2AMAPT | |
| SCHEMBL23120540 | 0.83 | DDB1 (0.57) | DDB1CRBNMEN1KMT2AMAPT | |
| SCHEMBL25079570 | 0.83 | DDB1 (0.52) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL30257613 | 0.83 | DDB1 (0.52) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL31255633 | 0.82 | DDB1 (0.53) | TPSAB1TPSD1TPSG1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31255623 | 0.81 | DDB1 (0.52) | TPSAB1TPSD1TPSG1DDB1CRBN | |
| SCHEMBL23120512 | 0.81 | HSD17B10 (0.50) | DDB1CRBNKMT2AGAAHPGD | |
| SCHEMBL29606381 | 0.81 | HSD17B10 (0.50) | DDB1CRBNKMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023531-A1 | ESTROGEN RECEPTOR DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |