Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120783 | 1.00 | MYC (0.47) | MYCCRBNDDB1KDM4EGAA | |
| SCHEMBL21409088 | 0.84 | ALDH1A1 (0.47) | CRBNDDB1KDM4EGAATDP1 | |
| SCHEMBL29606903 | 0.84 | DDB1 (0.58) | CRBNDDB1KDM4EGAATDP1 | |
| SCHEMBL21409149 | 0.84 | DDB1 (0.58) | CRBNDDB1KDM4EGAATDP1 | |
| SCHEMBL29606876 | 0.84 | CRBN (0.45) | CRBNDDB1KDM4EGAAALDH1A1 | |
| SCHEMBL21409269 | 0.84 | CRBN (0.45) | CRBNDDB1KDM4EGAAALDH1A1 | |
| SCHEMBL30816855 | 0.83 | DDB1 (0.47) | CRBNDDB1KDM4EGAAALDH1A1 | |
| SCHEMBL29201759 | 0.83 | DDB1 (0.47) | CRBNDDB1KDM4EGAAALDH1A1 | |
| SCHEMBL21408886 | 0.81 | KDM4E (0.50) | CRBNDDB1KDM4EGAALMNA | |
| SCHEMBL25214076 | 0.81 | TTR (0.48) | CRBNDDB1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114521196-A | Bifunctional group degradation agent and use method thereof | 诺华股份有限公司 | 2022-05-20 | — | — | CN | disclosed |