Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 13/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.61 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875559 | 1.00 | ENPP2 (0.64) | ENPP2DDB1CRBNMAPTNAMPT | |
| SCHEMBL29608800 | 0.91 | ENPP2 (0.76) | ENPP2DDB1CRBNMAPTMAPK1 | |
| SCHEMBL15874833 | 0.91 | ENPP2 (0.76) | ENPP2DDB1CRBNMAPTMAPK1 | |
| SCHEMBL30626024 | 0.91 | ENPP2 (0.76) | ENPP2DDB1CRBNMAPTMAPK1 | |
| SCHEMBL19001278 | 0.90 | ENPP2 (0.68) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL18818629 | 0.89 | DDB1 (0.68) | ENPP2DDB1CRBNMAPTMAPK1 | |
| SCHEMBL18819063 | 0.86 | DDB1 (0.62) | ENPP2DDB1CRBNMAPTMAPK1 | |
| SCHEMBL18525131 | 0.84 | ENPP2 (0.69) | ENPP2MAPK1 | |
| SCHEMBL18818336 | 0.84 | DDB1 (0.63) | DDB1CRBNMAPTMAPK1 | |
| SCHEMBL18536680 | 0.83 | ENPP2 (0.59) | ENPP2DDB1CRBNMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423759-B | Fused heteroaryl derivatives, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114423759-A | Condensed heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-04-29 | — | — | CN | disclosed |