SCHEMBL29608138

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	2/20	0.49

▸	C5AR1	P21730	1/20	0.48

▸	REN	P00797	7/20	0.48

▸	KDM1A	O60341	2/20	0.48

▸	OPRM1	P35372	6/20	0.47

▸	OPRK1	P41145	6/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29606988	0.96	C5AR1 (0.51)	APLNRC5AR1RENKDM1AOPRM1
SCHEMBL30788334	0.91	KDM1A (0.51)	APLNRC5AR1KDM1A
SCHEMBL29607221	0.91	C5AR1 (0.53)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29607931	0.91	C5AR1 (0.55)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29607547	0.90	REN (0.53)	APLNRC5AR1RENKDM1A
SCHEMBL29607774	0.88	APLNR (0.54)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29608843	0.87	C5AR1 (0.58)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29607540	0.87	C5AR1 (0.56)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29608840	0.87	C5AR1 (0.58)	APLNRC5AR1OPRM1OPRK1
SCHEMBL29608108	0.87	APLNR (0.55)	APLNRC5AR1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220120732-A1	TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES	RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL)	2022-04-21	—	—	US	disclosed