Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.69 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.69 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.69 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.69 |
| ▸ | FOS | P01100 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960696 | 0.92 | JUN (0.65) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL668045 | 0.90 | JUN (0.72) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL2960899 | 0.87 | JUN (0.59) | JUNUGT1A1UGT1A3UGT1A8PDE4A | |
| SCHEMBL2956891 | 0.85 | JUN (0.67) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL2966592 | 0.85 | JUN (0.57) | JUNUGT1A1UGT1A3UGT1A8PDE4A | |
| SCHEMBL2961264 | 0.85 | JUN (0.65) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL3039237 | 0.84 | JUN (0.55) | JUNUGT1A1UGT1A3UGT1A8PDE4A | |
| SCHEMBL2963278 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL2963281 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FOS | |
| SCHEMBL2960667 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | JUN 3/4885UGT1A1 1244/4885UGT1A3 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.