SCHEMBL2966592

SCHEMBL2966592

CCOC(=O)CCc1cc(C(=O)c2ccc(OC3CCCC3)cc2O)ccc1OCc1ccc(C(=O)OCC)c(OC)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.57
UGT1A1 P22309 1/20 0.57
UGT1A3 P35503 1/20 0.57
UGT1A8 Q9HAW9 1/20 0.57
KMT2A Q03164 5/20 0.41
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
HPGD P15428 1/20 0.38
PDE4B Q07343 2/20 0.37
PDE4D Q08499 2/20 0.37
HIF1A Q16665 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4C Q08493 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 4/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2960696 0.94 JUN (0.65) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2960899 0.90 JUN (0.59) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2956891 0.85 JUN (0.67) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2960859 0.85 JUN (0.69) JUNUGT1A1UGT1A3UGT1A8PDE4B
SCHEMBL2963266 0.85 JUN (0.60) JUNUGT1A1UGT1A3UGT1A8PDE4B
SCHEMBL2960177 0.84 JUN (0.56) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2967726 0.84 JUN (0.56) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL6829363 0.84 JUN (0.60) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2967854 0.82 JUN (0.59) JUNUGT1A1UGT1A3UGT1A8KMT2A
SCHEMBL2963264 0.81 JUN (0.59) JUNUGT1A1UGT1A3UGT1A8PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed