Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700806 | 0.88 | PPARD (0.46) | PPARDLPAR3LPAR2LPAR1 | |
| SCHEMBL9701504 | 0.88 | PPARD (0.46) | PPARDLPAR3LPAR2LPAR1 | |
| SCHEMBL9702638 | 0.88 | PPARD (0.46) | PPARDLPAR3LPAR2LPAR1 | |
| Water SCHEMBL9701709 | 0.86 | PPARD (0.44) | PPARDLPAR3LPAR2LPAR1 | |
| SCHEMBL9701509 | 0.86 | PPARD (0.47) | PPARDLPAR3LPAR2 | |
| SCHEMBL2960861 | 0.81 | PPARD (0.44) | PPARD | |
| SCHEMBL2954341 | 0.81 | LPAR3 (0.46) | PPARDLPAR3LPAR2CETPLPAR1 | |
| SCHEMBL2241949 | 0.75 | PPARD (0.75) | PPARDCETP | |
| SCHEMBL7451944 | 0.74 | PPARD (0.68) | PPARD | |
| SCHEMBL30956301 | 0.74 | PPARD (0.68) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060280719-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280719-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC43A1 | PPARD 3322/4885LPAR3 1651/4885LPAR2 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.