Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700806 | 0.98 | PPARD (0.46) | PPARDLPAR3LPAR2HSD17B10 | |
| SCHEMBL9701504 | 0.98 | PPARD (0.46) | PPARDLPAR3LPAR2HSD17B10 | |
| SCHEMBL9702638 | 0.98 | PPARD (0.46) | PPARDLPAR3LPAR2HSD17B10 | |
| Water SCHEMBL9701709 | 0.96 | PPARD (0.44) | PPARDLPAR3LPAR2HSD17B10 | |
| SCHEMBL2960868 | 0.86 | PPARD (0.53) | PPARDLPAR3LPAR2 | |
| SCHEMBL2959705 | 0.82 | CYP1A2 (0.41) | PPARDLPAR3LPAR2TSHR | |
| SCHEMBL7528050 | 0.81 | LMNA (0.48) | PPARDTSHR | |
| SCHEMBL2960861 | 0.81 | PPARD (0.44) | PPARDTSHRHSD17B10 | |
| SCHEMBL9701761 | 0.80 | LPAR3 (0.45) | PPARDLPAR3LPAR2TSHR | |
| SCHEMBL9702696 | 0.78 | LPAR3 (0.47) | PPARDLPAR3LPAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |