SCHEMBL296087

SCHEMBL296087

C=CC[Si](O[Si](CC=C)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15266412 0.90
SCHEMBL15266623 0.90
SCHEMBL15266830 0.88
SCHEMBL251739 0.83 ACHE (0.33) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL15266415 0.82
SCHEMBL15266655 0.81
SCHEMBL15302361 0.80 MEN1 (0.32) MEN1KMT2AL3MBTL1
SCHEMBL17886484 0.79
SCHEMBL6401841 0.78 ALDH1A1 (0.32) ALDH1A1TSHRSMN1; SMN2L3MBTL1CYP3A4
SCHEMBL18145378 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-9458177-B2 Oxazolidin-2-one compounds and uses thereof NOVARTIS AG (CH) 2016-10-04 US disclosed
EP-2817307-B1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF AS PI3KS INHIBITORS NOVARTIS AG (CH) 2016-07-13 EP disclosed
US-20150344735-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
US-20140378450-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2014-12-25 US disclosed
US-8865894-B2 Oxazolidin-2-one compounds and uses thereof NOVARTIS AG (CH) 2014-10-21 US disclosed
US-20130225574-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2013-08-29 US disclosed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP disclosed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US disclosed
US-7915369-B2 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2011-03-29 US disclosed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP disclosed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US disclosed
US-6156429-A POLYLACTONES; DEGRADABLE NON-TOXIC PRODUCTS USED FOR EXAMPLE FOR PACKAGING (FILMS) OR IN MEDICINE (IMPLANTS) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2000-12-05 US disclosed
US-5321150-A 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids ELI LILLY AND COMPANY (US) 1994-06-14 US disclosed
EP-0552552-A2 5-Deazafolic acid derivatives and their use as antineoplastics agents ELI LILLY AND COMPANY (US) 1993-07-28 EP disclosed
US-5159079-A 2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids ELI LILLY AND COMPANY (US) 1992-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378450-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF PIK3CA, PIK3CD, PIK3CB ALDH1A1 2637/4885TSHR 3875/4885KDM4E 3476/4885
US-20130225574-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF PIK3CA, PIK3CD, PIK3CB ALDH1A1 2637/4885TSHR 3875/4885KDM4E 3476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.