Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GALR2 | O43603 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736413 | 1.00 | RAB9A (0.68) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL2408726 | 0.86 | RAB9A (0.82) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL3243396 | 0.84 | NUDT1 (0.58) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL29609269 | 0.84 | NUDT1 (0.58) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL29609803 | 0.82 | NUDT1 (0.57) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL28229108 | 0.82 | NUDT1 (0.57) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL29610529 | 0.81 | RAB9A (0.73) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL28736336 | 0.81 | RAB9A (0.73) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL13288391 | 0.79 | MAPT (1.00) | RAB9AMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL28861466 | 0.78 | NPC1 (0.55) | RAB9AMAPTGAASMN1; SMN2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191774-B | Heterocyclic compound, preparation method and application thereof | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |