Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.50 |
| ▸ | FABP4 | P15090 | 9/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789968 | 1.00 | PIN1 (0.50) | PIN1FABP4TRPM8KDM4CKDM4A | |
| SCHEMBL1843417 | 0.90 | KDM4C (0.46) | PIN1FABP4TRPM8KDM4CKDM4A | |
| SCHEMBL2794949 | 0.89 | KDM4C (0.42) | PIN1FABP4TRPM8KDM4CKDM4A | |
| SCHEMBL1340548 | 0.86 | PIN1 (0.50) | PIN1FABP4KDM4C | |
| SCHEMBL1340154 | 0.86 | PIN1 (0.50) | PIN1FABP4KDM4C | |
| SCHEMBL1337775 | 0.86 | PIN1 (0.50) | PIN1FABP4KDM4C | |
| SCHEMBL2823313 | 0.85 | PIN1 (0.49) | PIN1TRPM8KDM4CKDM4AHTR2A | |
| SCHEMBL30335806 | 0.84 | PIN1 (0.59) | PIN1TRPM8KDM4CKDM4A | |
| SCHEMBL19926708 | 0.82 | ACHE (0.39) | PIN1HTR2AHTR2C | |
| SCHEMBL21788517 | 0.81 | PIN1 (0.51) | PIN1TRPM8HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022109741-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-02 | — | — | WO | disclosed |