SCHEMBL29610236

SCHEMBL29610236

Cc1ccc(-c2nc3ccccc3nc2C)cc1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.74
L3MBTL1 Q9Y468 4/20 0.67
KDM4E B2RXH2 8/20 0.61
ALDH1A1 P00352 7/20 0.61
POLB P06746 3/20 0.61
RAB9A P51151 2/20 0.61
MAPT P10636 2/20 0.61
CYP1A2 P05177 1/20 0.57
ADORA2A P29274 2/20 0.56
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 4/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NQO2 P16083 1/20 0.47
ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18136587 1.00 TDP1 (0.74) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL6341547 0.89 TDP1 (0.91) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL19169623 0.88 TDP1 (0.68) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL14733982 0.87 TDP1 (0.88) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL31135158 0.87 TDP1 (0.67) TDP1L3MBTL1KDM4EALDH1A1MAPT
SCHEMBL923856 0.87 TDP1 (0.67) TDP1L3MBTL1KDM4EALDH1A1MAPT
SCHEMBL8407630 0.85 TDP1 (1.00) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL24689425 0.84 CYP1A2 (0.54) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL18082983 0.84 KDM4E (0.65) TDP1L3MBTL1KDM4EALDH1A1POLB
SCHEMBL12904160 0.84 MAPK14 (0.62) TDP1L3MBTL1KDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119913525-A Electrochemical synthesis method of 3-aryl quinoxalinone compound 新疆大学 2025-05-02 CN disclosed
CN-114524773-B Synthesis method of aryl quinoxaline compound promoted by mechanical force 浙江工业大学 2024-05-28 CN disclosed
CN-113774411-B Method for electrochemically synthesizing aryl-substituted quinoxaline (ketone) derivative 浙江工业大学 2022-12-27 CN disclosed
CN-114524773-A Method for synthesizing aryl quinoxaline compound promoted by mechanical force 浙江工业大学 2022-05-24 CN disclosed