SCHEMBL14733982

SCHEMBL14733982

Cc1ccc(-c2ccc(-c3nc4ccccc4nc3-c3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.88
L3MBTL1 Q9Y468 5/20 0.71
KDM4E B2RXH2 8/20 0.65
ALDH1A1 P00352 7/20 0.65
RAB9A P51151 2/20 0.65
POLB P06746 2/20 0.65
MAPT P10636 2/20 0.65
LMNA P02545 2/20 0.55
GAA P10253 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
ADORA2A P29274 1/20 0.55
AKT1 P31749 1/20 0.52
AKT2 P31751 1/20 0.52
HPGD P15428 3/20 0.51
NQO2 P16083 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPK10 P53779 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341547 0.98 TDP1 (0.91) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL8407630 0.93 TDP1 (1.00) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL13727890 0.90 TDP1 (0.72) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL4750723 0.89 TDP1 (0.70) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL14819322 0.88 TDP1 (0.75) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL13071764 0.88 TDP1 (0.75) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL29610236 0.87 TDP1 (0.74) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL18136587 0.87 TDP1 (0.74) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL12722052 0.86 RAB9A (0.66) TDP1L3MBTL1KDM4EALDH1A1RAB9A
SCHEMBL12146757 0.86 TDP1 (0.71) TDP1L3MBTL1KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586740-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device using quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-19 US disclosed
US-20130049577-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed