Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369161 | 0.86 | APLNR (0.35) | — | |
| SCHEMBL13896334 | 0.85 | HSD11B1 (0.34) | — | |
| SCHEMBL2698129 | 0.85 | HSD11B1 (0.34) | — | |
| SCHEMBL2698125 | 0.85 | HSD11B1 (0.34) | — | |
| SCHEMBL13332051 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 | |
| SCHEMBL25534448 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 | |
| SCHEMBL168283 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 | |
| SCHEMBL22659622 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 | |
| SCHEMBL29418450 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 | |
| SCHEMBL4075573 | 0.81 | CA1 (0.34) | CA1CA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109698-A1 | MALT-1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2026-04-23 | — | — | US | disclosed |
| US-20250051327-A1 | MALT-1 MODULATORS | RECURSION PHARMACEUTICALS, INC. | 2025-02-13 | — | — | US | disclosed |
| EP-4228647-A1 | MALT1 MODULATORS AND USES THEREOF | Rheos Medicines, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081967-A1 | MALT1 MODULATORS AND USES THEREOF | RHEOS MEDICINES, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051327-A1 | MALT-1 MODULATORS | MALT1, BCL6, BCL9 | CA1 3472/4885CA2 3527/4885SIGMAR1 3977/4885 |
| US-20260109698-A1 | MALT-1 MODULATORS | MALT1, BCL6, BCL3 | CA1 624/4885CA2 1541/4885SIGMAR1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.