Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 11/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314271 | 1.00 | ADK (0.43) | ADKMETTL3PI4KAPI4K2BPI4K2A | |
| SCHEMBL20488584 | 0.85 | PRMT5 (0.45) | ADKMETTL3PRMT5WDR77 | |
| SCHEMBL30941168 | 0.84 | ADK (0.46) | ADKMETTL3PI4KAPI4K2BPI4K2A | |
| SCHEMBL25046663 | 0.81 | ADK (0.46) | ADKMETTL3SLC29A1 | |
| SCHEMBL31617994 | 0.80 | ADK (0.44) | ADKMETTL3PRMT5WDR77 | |
| SCHEMBL24314267 | 0.79 | ADK (0.43) | ADKMETTL3 | |
| SCHEMBL20488512 | 0.79 | ADK (0.43) | ADKMETTL3 | |
| SCHEMBL31617998 | 0.78 | ADK (0.44) | ADKMETTL3 | |
| SCHEMBL25048642 | 0.77 | ADK (0.42) | ADKMETTL3 | |
| SCHEMBL20488516 | 0.76 | PRMT5 (0.46) | ADKMETTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |