Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369213 | 0.86 | — | — | |
| SCHEMBL25420831 | 0.84 | WDR5 (0.32) | S1PR1 | |
| SCHEMBL30362104 | 0.83 | PARP1 (0.30) | — | |
| SCHEMBL25417886 | 0.83 | PDE2A (0.34) | S1PR1 | |
| SCHEMBL25417885 | 0.83 | PDE2A (0.34) | S1PR1 | |
| SCHEMBL30438245 | 0.83 | PDE2A (0.34) | S1PR1 | |
| SCHEMBL25417878 | 0.83 | PDE2A (0.34) | S1PR1 | |
| SCHEMBL31391864 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL18854460 | 0.81 | CHRNA1 (0.38) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL167261 | 0.81 | CHRNA1 (0.38) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673150-A2 | COMPOSITIONS AND METHODS FOR TREATING MALT1 ASSOCIATED DISEASES | Rarefied Biosciences, Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182599-A2 | COMPOSITIONS AND METHODS FOR TREATING MALT1 ASSOCIATED DISEASES | RAREFIED BIOSCIENCES, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| EP-4228647-A1 | MALT1 MODULATORS AND USES THEREOF | Rheos Medicines, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081967-A1 | MALT1 MODULATORS AND USES THEREOF | RHEOS MEDICINES, INC. (US) | 2022-04-21 | — | — | WO | disclosed |