Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.46 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.45 |
| ▸ | CALCR | P30988 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611810 | 0.96 | MAPK8 (0.49) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL29612257 | 0.95 | MAPK8 (0.51) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL29611735 | 0.92 | MAPK8 (0.53) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL29612063 | 0.90 | NTSR1 (0.49) | NTSR2NTSR1CAPN1SORT1CALCRL | |
| SCHEMBL31683759 | 0.88 | MAPK8 (0.49) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL29611738 | 0.86 | EPHA2 (0.50) | EPHA2CAPN1CALCRL | |
| SCHEMBL29611971 | 0.86 | CAPN1 (0.54) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL30095512 | 0.85 | RAMP3 (0.55) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL29612048 | 0.85 | NTSR1 (0.49) | NTSR2NTSR1SORT1XIAP | |
| SCHEMBL29612056 | 0.85 | NTSR1 (0.48) | NTSR2NTSR1CAPN1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12419824-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20220183950-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220183950-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | TYR, TELO2, MTX2 | MAPK8 3825/4885MAPK9 2916/4885MAPK10 2992/4885 |
| US-12419824-B2 | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | TYR, TELO2, MTX2 | MAPK8 3825/4885MAPK9 2916/4885MAPK10 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.