Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 19/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 13/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314226 | 1.00 | METTL3 (0.47) | METTL3PRMT5WDR77 | |
| SCHEMBL29611612 | 0.94 | PRMT5 (0.45) | METTL3PRMT5WDR77 | |
| SCHEMBL30642217 | 0.94 | PRMT5 (0.45) | METTL3PRMT5WDR77 | |
| SCHEMBL29610838 | 0.94 | PRMT5 (0.45) | METTL3PRMT5WDR77 | |
| SCHEMBL27090415 | 0.93 | METTL3 (0.47) | METTL3PRMT5WDR77 | |
| SCHEMBL24313852 | 0.90 | METTL3 (0.51) | METTL3PRMT5WDR77 | |
| SCHEMBL24314225 | 0.90 | ADORA3 (0.38) | METTL3PRMT5WDR77 | |
| SCHEMBL29610924 | 0.90 | ADORA3 (0.38) | METTL3PRMT5WDR77 | |
| SCHEMBL27090413 | 0.88 | PRMT5 (0.47) | METTL3PRMT5WDR77 | |
| SCHEMBL24313534 | 0.86 | METTL3 (0.58) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |