Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18953141 | 1.00 | SIRT6 (0.45) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL11922558 | 0.94 | TDP1 (0.45) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1640894 | 0.89 | SIRT6 (0.48) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL29679513 | 0.89 | SIRT6 (0.48) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL2895340 | 0.87 | PDGFRB (0.50) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL13107196 | 0.84 | PDGFRB (0.51) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL29569855 | 0.83 | SIRT6 (0.44) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL20501210 | 0.83 | SIRT6 (0.44) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL2609072 | 0.83 | SIRT6 (0.44) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL11922583 | 0.83 | TDP1 (0.50) | SIRT6PDGFRBFGFR1PDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208260-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | The Scripps Research Institute (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022051765-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-03-10 | — | — | WO | disclosed |