SCHEMBL29612183

SCHEMBL29612183

CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(N)=O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.57
BACE2 Q9Y5Z0 2/20 0.57
CASP1 P29466 1/20 0.56
IL23R Q5VWK5 9/20 0.53
OPRD1 P41143 1/20 0.52
PTPN1 P18031 1/20 0.51
TFPI P10646 1/20 0.51
GRIA1 P42261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29611501 0.96 BACE1 (0.58) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL29611415 0.95 BACE1 (0.59) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL29611561 0.94 BACE1 (0.58) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL29611494 0.94 BACE1 (0.58) BACE1BACE2CASP1IL23RTFPI
SCHEMBL29611329 0.94 CASP1 (0.55) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL29611340 0.94 TFPI (0.53) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL29611951 0.93 BACE1 (0.54) BACE1BACE2IL23RPTPN1TFPI
SCHEMBL29611454 0.92 PTPN1 (0.60) BACE1BACE2CASP1IL23ROPRD1
SCHEMBL30918770 0.92 IL23R (0.62) IL23RTFPI
SCHEMBL24739787 0.92 CASP1 (0.53) BACE1BACE2CASP1IL23ROPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12419824-B2 Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-09-23 US claimed
US-20220183950-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-06-16 US claimed
US-12419824-B2 Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-09-23 US disclosed
EP-4573103-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES Lubrizol Advanced Materials, Inc. (US) 2025-06-25 EP disclosed
WO-2024038345-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-02-22 WO disclosed
US-20220183950-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220183950-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES TYR, TELO2, MTX2 BACE1 3288/4885BACE2 3110/4885CASP1 3410/4885
US-12419824-B2 Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes TYR, TELO2, MTX2 BACE1 3288/4885BACE2 3110/4885CASP1 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.