Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515031 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPTKAT2BGSTM2BCL6 | |
| SCHEMBL420519 | 0.91 | MAPT (0.54) | ALDH1A1MAPTKAT2BGSTM2RAB9A | |
| SCHEMBL6896294 | 0.88 | PRSS1 (0.53) | ALDH1A1MAPTKAT2BGSTM2PRSS1 | |
| SCHEMBL17678158 | 0.85 | SMN1; SMN2 (0.57) | ALDH1A1MAPTKAT2B | |
| SCHEMBL17743314 | 0.83 | PRSS1 (0.56) | ALDH1A1MAPTKAT2BGSTM2PRSS1 | |
| SCHEMBL31638149 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTKAT2BGSTM2BCL6 | |
| SCHEMBL17378355 | 0.82 | KAT2B (0.49) | ALDH1A1MAPTKAT2B | |
| SCHEMBL1842548 | 0.82 | HCAR3 (0.52) | ALDH1A1MAPTKAT2BRAB9A | |
| SCHEMBL1046670 | 0.82 | LMNA (0.57) | ALDH1A1MAPTKAT2BRAB9ATDP1 | |
| SCHEMBL14247598 | 0.81 | MAPT (0.53) | ALDH1A1MAPTKAT2BRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |