Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23063484 | 0.81 | KDM4E (0.44) | MAPTPOLBALDH1A1MAOAMAOB | |
| SCHEMBL23063016 | 0.81 | GCK (0.41) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23042415 | 0.78 | HTT (0.43) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL23042410 | 0.78 | HDAC1 (0.43) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL29612543 | 0.78 | HDAC1 (0.43) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL23042452 | 0.77 | L3MBTL1 (0.45) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL23042417 | 0.76 | MEN1 (0.41) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL654958 | 0.76 | MAPT (0.77) | MAPTPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL23042589 | 0.76 | NPC1 (0.38) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29729458 | 0.76 | NPC1 (0.38) | MAPTALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |