Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042410 | 1.00 | HDAC1 (0.43) | HDAC1HDAC8HDAC6KDM4EPDE7A | |
| SCHEMBL23042415 | 0.87 | HTT (0.43) | HDAC1HDAC8HDAC6KDM4EPDE7A | |
| SCHEMBL29612474 | 0.83 | HDAC1 (0.39) | HDAC1HDAC8HDAC6KDM4EPDE7A | |
| SCHEMBL23042369 | 0.83 | HDAC1 (0.39) | HDAC1HDAC8HDAC6KDM4EPDE7A | |
| SCHEMBL29612551 | 0.82 | PPARG (0.53) | KDM4EALDH1A1MEN1KMT2APIN1 | |
| SCHEMBL28730677 | 0.82 | PPARG (0.53) | KDM4EALDH1A1MEN1KMT2APIN1 | |
| SCHEMBL11291316 | 0.82 | PIN1 (0.51) | KDM4EPDE7AALDH1A1MEN1KMT2A | |
| SCHEMBL10966065 | 0.80 | KDM4E (0.43) | HDAC1HDAC8HDAC6KDM4EPDE7A | |
| SCHEMBL23042417 | 0.78 | MEN1 (0.41) | KDM4EPDE7AALDH1A1MEN1KMT2A | |
| SCHEMBL29612527 | 0.78 | MAPT (0.50) | HDAC1HDAC8HDAC6KDM4EPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |