Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730648 | 1.00 | DGAT1 (0.42) | DGAT1NPC1ELANEMAPTHTR2A | |
| SCHEMBL23042585 | 0.85 | NPC1 (0.36) | DGAT1NPC1ELANEMAPTHTR2A | |
| SCHEMBL29612449 | 0.85 | NPC1 (0.36) | DGAT1NPC1ELANEMAPTHTR2A | |
| SCHEMBL4312796 | 0.85 | DGAT1 (0.43) | DGAT1NPC1ELANEMAPTDYRK1A | |
| SCHEMBL2030421 | 0.84 | DGAT1 (0.43) | DGAT1NPC1ELANEMAPTDYRK1A | |
| SCHEMBL20163415 | 0.84 | DGAT1 (0.47) | DGAT1NPC1ELANEMAPTF2RL1 | |
| SCHEMBL3355074 | 0.84 | DGAT1 (0.43) | DGAT1NPC1ELANEMAPTDYRK1A | |
| SCHEMBL23042316 | 0.82 | DGAT1 (0.44) | DGAT1NPC1ELANEMAPTHTR2A | |
| SCHEMBL30459885 | 0.82 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL17682976 | 0.82 | DGAT1 (0.34) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |