Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.49 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942660 | 1.00 | CTSD (0.51) | CTSDKMT2AMAPTMEN1TP53 | |
| SCHEMBL29612951 | 0.85 | CTSD (0.53) | CTSDKMT2AMAPTMEN1HSPD1 | |
| SCHEMBL28760749 | 0.85 | CTSD (0.53) | CTSDKMT2AMAPTMEN1HSPD1 | |
| SCHEMBL29612984 | 0.83 | CTSD (0.61) | CTSDKMT2AMAPTMEN1TP53 | |
| SCHEMBL28760759 | 0.83 | CTSD (0.61) | CTSDKMT2AMAPTMEN1TP53 | |
| SCHEMBL2742720 | 0.78 | MAPT (0.51) | CTSDKMT2AMAPTMEN1TP53 | |
| SCHEMBL28760788 | 0.77 | CTSD (0.66) | CTSDKMT2AMAPTMEN1POLB | |
| SCHEMBL29612959 | 0.77 | CTSD (0.66) | CTSDKMT2AMAPTMEN1POLB | |
| SCHEMBL29612953 | 0.77 | CTSD (0.60) | CTSDKMT2AMAPTMEN1HSPD1 | |
| SCHEMBL12670548 | 0.76 | MAPT (0.50) | KMT2AMAPTMEN1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524780-A | Mercaptobenzothiazole urea compound, pharmaceutical preparation, preparation method and application | 绍兴市上虞区武汉理工大学高等研究院 | 2022-05-24 | — | — | CN | disclosed |