Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760809 | 1.00 | CTSD (0.64) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL29612961 | 0.90 | HSPD1 (0.69) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL28760743 | 0.90 | HSPD1 (0.69) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL28760759 | 0.89 | CTSD (0.61) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL29612984 | 0.89 | CTSD (0.61) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL29612959 | 0.85 | CTSD (0.66) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL28760788 | 0.85 | CTSD (0.66) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL28760740 | 0.84 | CTSD (0.60) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL29612953 | 0.84 | CTSD (0.60) | CTSDHSPD1HSPE1MAPTMEN1 | |
| SCHEMBL24118877 | 0.83 | CTSD (0.72) | CTSDHSPD1HSPE1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524780-A | Mercaptobenzothiazole urea compound, pharmaceutical preparation, preparation method and application | 绍兴市上虞区武汉理工大学高等研究院 | 2022-05-24 | — | — | CN | disclosed |