Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 9/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368750 | 1.00 | KCNH2 (0.36) | KCNH2RORCFASNCCR1PTGDR2 | |
| SCHEMBL19786031 | 0.91 | RORC (0.36) | KCNH2RORCFASNCCR1PTGDR2 | |
| SCHEMBL28720859 | 0.89 | RORC (0.36) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL29613318 | 0.89 | RORC (0.36) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL29613311 | 0.89 | RORC (0.36) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL21368604 | 0.89 | RORC (0.36) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL21368605 | 0.89 | RORC (0.36) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL21354266 | 0.89 | KCNH2 (0.39) | KCNH2RORCFASNPTGDR2TP53 | |
| SCHEMBL21368883 | 0.88 | RORC (0.38) | KCNH2RORCCCR1PTGDR2 | |
| SCHEMBL29613289 | 0.88 | RORC (0.38) | KCNH2RORCCCR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | disclosed |