Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PPM1A | P35813 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289697 | 0.82 | ACHE (0.67) | ACHECYP1A2CYP2A6PPM1ACRHBP | |
| SCHEMBL27902298 | 0.76 | CYP2A6 (0.65) | CYP1A2CYP2A6RAD52HNF4AKDM4E | |
| SCHEMBL9040087 | 0.75 | CYP1A2 (0.72) | CYP1A2CYP2A6RAD52KDM4EALDH1A1 | |
| SCHEMBL29613269 | 0.75 | ALDH1A1 (0.50) | CYP1A2CYP2A6RAD52KDM4EALDH1A1 | |
| SCHEMBL7896191 | 0.75 | ALDH1A1 (0.50) | CYP1A2CYP2A6RAD52KDM4EALDH1A1 | |
| SCHEMBL3137389 | 0.74 | CYP2A6 (0.62) | CYP1A2CYP2A6RAD52HNF4AKDM4E | |
| SCHEMBL12277498 | 0.74 | CYP2A6 (0.62) | CYP1A2CYP2A6RAD52HNF4AKDM4E | |
| SCHEMBL12259995 | 0.74 | CYP2A6 (0.62) | CYP1A2CYP2A6RAD52HNF4AKDM4E | |
| SCHEMBL12473666 | 0.73 | CYP1A2 (0.69) | CYP1A2CYP2A6RAD52KDM4EALDH1A1 | |
| SCHEMBL12277720 | 0.73 | CYP1A2 (0.69) | CYP1A2CYP2A6RAD52KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |