Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK9 | P50750 | 4/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223018 | 1.00 | EGFR (0.48) | EGFRTNFSF11CDK2CCNT1CCNE1 | |
| SCHEMBL15647363 | 0.91 | EGFR (0.45) | EGFRTNFSF11CDK2CCNT1CCNE1 | |
| SCHEMBL16665592 | 0.86 | EGFR (0.51) | EGFRCDK2CCNT1CCNE1CDK9 | |
| SCHEMBL29613438 | 0.86 | EGFR (0.51) | EGFRCDK2CCNT1CCNE1CDK9 | |
| SCHEMBL16655389 | 0.86 | EGFR (0.48) | EGFRCDK2CCNT1CCNE1CDK9 | |
| SCHEMBL29174622 | 0.84 | EGFR (0.45) | EGFRCDK9POLBALDH1A1KMT2A | |
| SCHEMBL29174730 | 0.83 | EGFR (0.46) | EGFRCDK1KMT2ACA12CA1 | |
| SCHEMBL15648478 | 0.83 | EGFR (0.47) | EGFRCDK2CCNT1CCNE1CDK9 | |
| SCHEMBL29174579 | 0.82 | EGFR (0.43) | EGFRTNFSF11CDK2CCNT1CCNE1 | |
| SCHEMBL29174659 | 0.82 | EGFR (0.45) | EGFRCDK9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |