SCHEMBL29613855

SCHEMBL29613855

O=C1NC2CSC(CCCCC(=O)N3C(=O)CC(S(=O)(=O)O)C3=O)C2N1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.57
MEN1 O00255 1/20 0.57
ABL1 P00519 1/20 0.57
LMNA P02545 1/20 0.57
PKM P14618 1/20 0.57
IDE P14735 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
RIN1 Q13671 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CA12 O43570 8/20 0.51
CA1 P00915 8/20 0.51
CA2 P00918 8/20 0.51
CA9 Q16790 8/20 0.51
HLCS P50747 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979297 0.85 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL14417216 0.85 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL17385535 0.85 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL1549117 0.84 TDP1 (0.57) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1023525 0.84 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1270216 0.84 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL24406816 0.81 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL14453893 0.81 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL3348232 0.80 CA12 (0.51) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL2192463 0.80 TDP1 (0.60) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119265122-A Antigen-specific T cell screening method based on intercellular interaction screening platform 人工智能与数字经济广东省实验室(深圳) 2025-01-07 CN claimed
CN-119555930-A Photo-activated chemiluminescence detection reagent composition, kit, detection method and device 科美诊断技术股份有限公司 2025-03-04 CN disclosed
CN-119265122-A Antigen-specific T cell screening method based on intercellular interaction screening platform 人工智能与数字经济广东省实验室(深圳) 2025-01-07 CN disclosed
US-20230414754-A1 CONDITIONAL CONTROL OF UNIVERSAL CAR T CELLS THROUGH STIMULUS-REACTIVE ADAPTORS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-12-28 US disclosed
CN-117286289-A Primer pair, gRNA, kit and method for detecting African swine fever virus 山东农业大学 2023-12-26 CN disclosed
EP-4240772-A1 CONDITIONAL CONTROL OF UNIVERSAL CAR T CELLS THROUGH STIMULUS-REACTIVE ADAPTORS University of Pittsburgh - of the Commonwealth System of Higher Education (US) 2023-09-13 EP disclosed
CN-116419931-A Condition control of universal CAR T cells by stimulation of reactive adaptors 联邦高等教育系统匹兹堡大学 2023-07-11 CN disclosed
US-20220170859-A1 PARTICLE LABELING REAGENT, PARTICLE DYEING METHOD, AND MICROSCOPIC SYSTEM Sony Group Corporation (JP) 2022-06-02 US disclosed
WO-2022099065-A1 CONDITIONAL CONTROL OF UNIVERSAL CAR T CELLS THROUGH STIMULUS-REACTIVE ADAPTORS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-05-12 WO disclosed