Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776425 | 1.00 | PTGER4 (0.36) | PTGER4PTGDR2NPY5REGLN1HCRTR1 | |
| SCHEMBL22776453 | 0.92 | PTGER4 (0.34) | PTGER4PTGDR2NPY5RHCRTR1HCRTR2 | |
| SCHEMBL22777088 | 0.91 | PTGER4 (0.35) | PTGER4PTGDR2NPY5REGLN1P2RY14 | |
| SCHEMBL22776455 | 0.88 | HTR4 (0.34) | PTGER4NPY5REGLN1 | |
| SCHEMBL22791294 | 0.85 | PTGER4 (0.34) | PTGER4PTGDR2NPY5RHCRTR1HCRTR2 | |
| SCHEMBL22776491 | 0.83 | FPR1 (0.33) | PTGER4PTGDR2 | |
| SCHEMBL22777090 | 0.83 | PDE4A (0.37) | PTGER4 | |
| SCHEMBL22776540 | 0.81 | PTGER4 (0.42) | PTGER4PTGDR2NPY5RHCRTR1HCRTR2 | |
| SCHEMBL22776728 | 0.79 | HIF1A (0.35) | EGLN1 | |
| SCHEMBL29527365 | 0.79 | HIF1A (0.35) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983412-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | Teon Therapeutics, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |