Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 8/20 | 0.53 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.53 |
| ▸ | ABL2 | P42684 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 6/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307188 | 1.00 | CDK1 (0.55) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL19307144 | 0.83 | ABL1 (0.57) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL19307164 | 0.83 | ABL1 (0.65) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL29614886 | 0.83 | ABL1 (0.57) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL29614931 | 0.83 | ABL1 (0.65) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL19316712 | 0.80 | FGFR4 (0.59) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL29614800 | 0.80 | ABL1 (0.51) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL19307131 | 0.80 | ABL1 (0.51) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL27927274 | 0.78 | ABL1 (0.60) | CDK1CDK2CDK8ABL1FGFR4 | |
| SCHEMBL23732816 | 0.76 | ABL1 (0.53) | CDK1CDK2CDK8ABL1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | CORNELL UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | PTGES, PTGS1, PTGES2 | CDK1 3629/4885CDK2 3011/4885CDK8 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.