Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.51 |
| ▸ | ABL2 | P42684 | 6/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307090 | 1.00 | ABL1 (0.51) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL24449243 | 0.89 | ABL1 (0.56) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL29614931 | 0.88 | ABL1 (0.65) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL19307164 | 0.88 | ABL1 (0.65) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL19307229 | 0.82 | ABL1 (0.45) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL29614852 | 0.82 | ABL1 (0.45) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL20214559 | 0.81 | FGFR4 (0.53) | ABL1ABL2MAPK14FGFR4RET | |
| SCHEMBL23732816 | 0.79 | ABL1 (0.53) | ABL1ABL2NTRK1NTRK3NTRK2 | |
| SCHEMBL19316719 | 0.79 | ABL1 (0.55) | ABL1ABL2MAPK14FGFR4CDK1 | |
| SCHEMBL24448260 | 0.78 | ABL1 (0.73) | ABL1ABL2NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | CORNELL UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | PTGES, PTGS1, PTGES2 | ABL1 4516/4885ABL2 2755/4885NTRK1 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.