Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.44 |
| ▸ | LPL | P06858 | 7/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20050714 | 1.00 | AKT1 (0.45) | AKT1AKT2LIPGLPLDGAT1 | |
| SCHEMBL806784 | 0.83 | LIPG (0.60) | LIPGLPLIRAK4 | |
| SCHEMBL488172 | 0.82 | LIPG (0.57) | AKT1AKT2LIPGLPLDGAT1 | |
| SCHEMBL31456342 | 0.81 | LIPG (0.58) | LIPGLPLIRAK4 | |
| SCHEMBL20023287 | 0.81 | LIPG (0.58) | LIPGLPLIRAK4 | |
| SCHEMBL31456345 | 0.81 | LIPG (0.58) | LIPGLPLIRAK4 | |
| SCHEMBL21142655 | 0.81 | LPL (0.42) | AKT1AKT2LIPGLPLDGAT1 | |
| SCHEMBL15495620 | 0.80 | LIPG (0.56) | LIPGLPLIRAK4 | |
| SCHEMBL18239827 | 0.79 | LIPG (0.43) | LIPGLPLDGAT1IRAK4 | |
| SCHEMBL3362199 | 0.78 | LIPG (0.70) | LIPGLPLDGAT1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803963-B | Cyano-substituted heterocycles having USP30 inhibitor activity | 特殊治疗有限公司 | 2022-04-26 | — | — | CN | disclosed |