Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615020 | 0.95 | SMN1; SMN2 (0.56) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL8608304 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL6427034 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL6427442 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL14471579 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL9276855 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL8608960 | 0.91 | LMNA (0.55) | ALDH1A1LMNAHDAC1CYP3A4KMT2A | |
| SCHEMBL28736296 | 0.90 | LMNA (0.63) | ALDH1A1LMNAHDAC1KMT2AMEN1 | |
| SCHEMBL28736297 | 0.90 | LMNA (0.63) | ALDH1A1LMNAHDAC1KMT2AMEN1 | |
| SCHEMBL29614989 | 0.88 | NPC1 (0.56) | ALDH1A1LMNAHDAC1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092730-B | Method for preparing optically active alpha-hydroxy-beta-amino acid compound | 西华大学 | 2022-05-13 | — | — | CN | disclosed |