Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.55 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024990 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1NPC1SRCPRKAB2 | |
| SCHEMBL22918726 | 0.93 | HRH3 (0.57) | KDM4EALDH1A1NPC1SRCCYP1A2 | |
| SCHEMBL29615558 | 0.93 | HRH3 (0.57) | KDM4EALDH1A1NPC1SRCCYP1A2 | |
| SCHEMBL29615643 | 0.87 | LTA4H (0.57) | KDM4EALDH1A1KMT2ALTA4H | |
| SCHEMBL22918728 | 0.87 | LTA4H (0.54) | KDM4EALDH1A1KMT2ALTA4H | |
| SCHEMBL29615365 | 0.87 | LTA4H (0.54) | KDM4EALDH1A1KMT2ALTA4H | |
| SCHEMBL22919001 | 0.87 | LTA4H (0.57) | KDM4EALDH1A1KMT2ALTA4H | |
| SCHEMBL2023773 | 0.84 | MEN1 (0.55) | KDM4EALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL15260226 | 0.83 | KDM4E (0.66) | KDM4EALDH1A1NPC1SRCCA12 | |
| SCHEMBL31372502 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1NPC1SRCCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |