Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22918759 | 1.00 | HRH3 (0.54) | HRH3KDM4EL3MBTL1MAOBKCNH2 | |
| SCHEMBL29615643 | 0.92 | LTA4H (0.57) | KDM4E | |
| SCHEMBL22919001 | 0.92 | LTA4H (0.57) | KDM4E | |
| SCHEMBL22918728 | 0.89 | LTA4H (0.54) | KDM4E | |
| SCHEMBL29615365 | 0.89 | LTA4H (0.54) | KDM4E | |
| SCHEMBL22918755 | 0.88 | HRH3 (0.58) | HRH3KDM4EL3MBTL1SIGMAR1 | |
| SCHEMBL22918726 | 0.87 | HRH3 (0.57) | HRH3KDM4EKCNH2SIGMAR1 | |
| SCHEMBL29615558 | 0.87 | HRH3 (0.57) | HRH3KDM4EKCNH2SIGMAR1 | |
| SCHEMBL1824079 | 0.82 | KDM4E (0.56) | HRH3KDM4EL3MBTL1ACHERAD52 | |
| SCHEMBL2023773 | 0.81 | MEN1 (0.55) | HRH3KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955500-A | 4- (Imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4003992-A1 | 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL) -PYRIMIDINE DERIVATIVES | Merck Patent GmbH (DE) | 2022-06-01 | — | — | EP | disclosed |
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |