Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407201 | 1.00 | HCAR1 (0.52) | HCAR1KMOHCAR2CES2CES1 | |
| SCHEMBL13406398 | 0.88 | HCAR1 (0.44) | HCAR1KMOHCAR2HTR7 | |
| SCHEMBL4392929 | 0.88 | KMO (0.55) | KMOHCAR2MRGPRX4TTRCREBBP | |
| SCHEMBL184302 | 0.86 | KMO (0.53) | KMOHCAR2MRGPRX4TTRCREBBP | |
| SCHEMBL30597930 | 0.83 | PARP1 (0.44) | KMOCES2CES1NPY5R | |
| SCHEMBL3244198 | 0.83 | PARP1 (0.44) | KMOCES2CES1NPY5R | |
| SCHEMBL19404230 | 0.83 | HCAR1 (0.40) | HCAR1KMOHCAR2CES2CES1 | |
| SCHEMBL13646149 | 0.82 | P2RY14 (0.45) | HCAR1 | |
| SCHEMBL13646147 | 0.82 | P2RY14 (0.45) | HCAR1 | |
| SCHEMBL24851934 | 0.79 | HSD17B10 (0.44) | NPY5RL3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423741-B | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-3999493-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2022-05-25 | — | — | EP | disclosed |