Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680679 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL2912873 | 0.89 | KDM4E (0.73) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL22489533 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL21216702 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29691521 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL30034172 | 0.86 | KDM4E (0.60) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL12042607 | 0.86 | KDM4E (0.80) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL2315127 | 0.86 | MAPT (0.64) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3497730 | 0.86 | KDM4E (0.64) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL20110922 | 0.83 | PRKCI (0.53) | KDM4EMAPTUSP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999493-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2022-05-25 | — | — | EP | disclosed |