SCHEMBL2912873

SCHEMBL2912873

COC(=O)c1ccc(N)c(C(=O)OC)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.73
ALDH1A1 P00352 8/20 0.73
HSD17B10 Q99714 5/20 0.73
HPGD P15428 5/20 0.73
MAPT P10636 5/20 0.73
GAA P10253 4/20 0.73
GLA P06280 1/20 0.73
CASP1 P29466 1/20 0.73
CASP7 P55210 1/20 0.73
ATM Q13315 1/20 0.73
ALOX15 P16050 2/20 0.64
TSHR P16473 1/20 0.64
CFTR P13569 1/20 0.58
NPC1 O15118 3/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29615917 0.89 ALDH1A1 (0.64) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL2315127 0.89 MAPT (0.64) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL3497730 0.89 KDM4E (0.64) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL30034172 0.89 KDM4E (0.60) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL2722810 0.89 KDM4E (0.60) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL1680679 0.89 ALDH1A1 (0.64) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL25232739 0.86 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL21216702 0.86 ALDH1A1 (0.60) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL22489533 0.86 ALDH1A1 (0.60) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL29691521 0.86 ALDH1A1 (0.60) KDM4EALDH1A1HSD17B10HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161848-A UV (ultraviolet) light-cured adhesive, preparation method and application 苏州吉格邦新材料科技有限公司 2024-12-20 CN claimed
CN-118026869-A 4-Amino isophthalic acid dimethyl ester-tetracyanobenzene eutectic crystal and preparation method and application thereof 天津大学 2024-05-14 CN claimed
CN-104559905-A Food-additive-resistant flexible packaging compound binder and preparation method thereof BEIJING COMENS NEW MAT CO LTD 2015-04-29 CN claimed
CN-119161848-A UV (ultraviolet) light-cured adhesive, preparation method and application 苏州吉格邦新材料科技有限公司 2024-12-20 CN disclosed
CN-118026869-A 4-Amino isophthalic acid dimethyl ester-tetracyanobenzene eutectic crystal and preparation method and application thereof 天津大学 2024-05-14 CN disclosed
CN-118026869-A 4-Amino isophthalic acid dimethyl ester-tetracyanobenzene eutectic crystal and preparation method and application thereof 天津大学 2024-05-14 CN disclosed
CN-118026869-A 4-Amino isophthalic acid dimethyl ester-tetracyanobenzene eutectic crystal and preparation method and application thereof 天津大学 2024-05-14 CN disclosed
EP-3880666-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-06-28 EP disclosed
US-20230024859-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-01-26 US disclosed
US-20230024859-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-01-26 US disclosed
CN-114163400-A Cyclohexanedione-benzothiadiazine compound and application thereof 东莞市东阳光农药研发有限公司 2022-03-11 CN disclosed
EP-0791576-A2 Leukotriene antagonistic benzoic acid derivatives BAYER AG (DE) 1997-08-27 EP disclosed
US-5340808-A Fused pyridazinoquinazolone derivatives as neurotrophic agents WARNER LAMBERT COMPANY (US) 1994-08-23 US disclosed
WO-1994011373-A1 PYRIDAZINOQUINAZOLONE DERIVATIVES AS NEUROTROPHIC AGENTS WARNER-LAMBERT COMPANY (US) 1994-05-26 WO disclosed
EP-0039312-B1 COLOUR PHOTOPGRAPHIC MATERIAL FOR THE SILVER-DYE BLEACHING PROCESS, PROCESS FOR THE PRODUCTION OF THIS MATERIAL AND ITS USE IN THE PRODUCTION OF PHOTOGRAPHIC IMAGES CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
EP-0039312-A1 Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed
US-4268510-A DEMETHANIZATION, METABOLISM, RUMEN IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 US disclosed
US-4251531-A ANTIALLERGENS FARMITALIA CARLO ERBA S.P.A. (IT) 1981-02-17 US disclosed
US-4159330-A ANTIALLERGENS CARLO ERBA S.P.A. (IT) 1979-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024859-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NLRP1, NLRP3, NOD1 KDM4E 4507/4885ALDH1A1 2065/4885HSD17B10 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.